Endocrine Abstracts

Normocalcemic primary hyperparathyroidism (nPHPT) is still a poorly understood entity, characterized by increased circulating parathormone (PTH) and normal total and ionic calcium, excluding secondary causes.Aim: To characterize the cases of nPHPT detected for a whole year from laboratory records of PTH in a tertiary referral centre, with the purpose of assessing a preliminary estimation and describing their main features.Material ...

Introduction: Severe hypoglycemia and retinopathy are two of the main complications of diabetes mellitus (DM). Traditionally, glycosylated hemoglobin (or A1C) has been used as the gold standard measurement of glycemic control; however, there is a significant percentage of complications riskassociated with the evolution of diabetes that is not fully explained by this single marker. Short and long-term glycemic variability has been postulated as one of the main variables that co...

Background: Although obesity and has been associated with COVID-19 mortality, the absolute and relative risks for Type 2 diabetes (DM2) is unknown. The aim of this study was to analyse metabolic characteristics of patients infected by COVID-19 hospitalised and evaluate whether DM2 have an impact in this group of patients.Methods: We retrospectively analysed data of COVID-19 patients hospitalized to a large academic hospital system in Zaragoza between Mar...

Introduction: Ectopic Cushing Syndrome (ECS) is a rare disease associated with significant comorbidity. Among the causes of Cushing’s syndrome (CS), ACTH-producing extrahypophyseal tumours are rarely reported. The aim of our study is to describe the clinical, diagnostic and therapeutic characteristics of patients with ECS treated in our Endocrinology department over a 15-year period.Methods: A cross-sectional unicentric retrospective study was desi...

Aim: Atherosclerotic cardiovascular disease, defined as myocardial infarction (MI), cerebrovascular accident (CVA), peripheral artery disease (PAD), is the main cause of morbidity and mortality in people with diabetes mellitus (DM) and the main cause of health expenditure in these patients.Like in other parts of the world, a prospective study of the Asturian population showed that the mortality risk due to cardiovascular diseases was significantly higher...

Introduction: One of the often-discussed topics in the management guidelines for Type 1 Diabetes Mellitus (T1DM) is the ideal time gap that should exist between patient check-ups. A period of three to six months is usually recommended, which sometimes is difficult to achieve due to the high number of patients. But to what extent does the time gap between appointments in the follow-up of T1DM patients affect their diabetes’ control?Objectives: To kn...

Objectives: We studied whether the postoperative serum thyroglobulin (TG) basal levels before treatment with I131 (baseline TG) could be related with the response to treatment. We consider the excellent response as the absence of clinical, biochemical disease (undetectable TG and anti-thyroglobulin antibodies AcTG negative) and/or structural disease.Material and Methods: This is an observational study that includes 100 patients with differentiated thyroi...

There is a direct relation between the degree of glycemic control and the incidence and progression of diabetic complications. In addition improving glycemic control improves diabetic complications.Aim: To assess the degree of glycemic control, according to published guidelines, in treated type 2 diabetes mellitus patients who live in a district of Madrid, Spain.Methods: Cross-sectional study in 501 consecutive patients with T2DM w...

Introduction: Bariatric surgery has proved to be effective in the management of morbid obesity. Our purpose was to compare the results obtained with adjustable gastric banding (GB) and Roux-en-Y Gastric Bypass (RYGB) during 2 years of follow-up after surgery, with regard to anthropometric parameters and related comorbidities.Methods: We evaluated prospectively patients who underwent GB and RYGB between 2004 and 2010 and compared the evolution of anthropo...

Aims (objectives): Energy intake and expenditure are regulated by different signals. One of the molecules implicated is islet amyloid polypeptide (IAPP or amylin), one of the major secretory products of β-cells of the pancreatic islets of Langerhans. It is a peptide that inhibits insulin and glucagon secretion, and can also act through the brain decreasing food intake and inhibiting gastric emptying. In this study, we investigated the potential effects of the chronic cent...